When it comes to anti-ageing skincare, results matter – but so does the experience. After all, no one wants to commit to a serum that feels sticky, smells medicinal, or pills under makeup; no matter how effective it claims to be – let’s face it, you’re never using it.
The best anti-ageing serums in 2025 don’t just deliver firmer, brighter, more youthful-looking skin, they also make your skincare routine feel like a treat rather than a chore!
Best Anti-Ageing Serums To Try
Nuxe Super Serum [10] Award-winning!
Best for: Botanical-based solution that works
Since its global debut in 2021, the Super Serum [10] has taken the beauty world by storm, earning 13 prestigious beauty awards and securing its position as the No. 1 microfluidic serum in French pharmacies. It’s so popular, one is sold every minute.
Offering the benefits of 10 serums in one, such as smoothing out wrinkles, firming, and replumping the skin, this serum is clinically proven to make your skin act 10 years younger.
It is crafted with patented Edelweiss botanical cells, 100% natural hyaluronic acid, niacinamide, and fractionated botanical oils, encapsulated in over 3,800 golden micro-spheres per bottle using cutting-edge silicone-free microfluidic technology.
You’ll appreciate its lightweight, non-greasy formula that provides an immediate fresh glow along with a subtle botanical scent.
Nuxe Super Serum [10] retails for S$141.20 and is available at Guardian, Shopee, and Lazada.
But Better Brighter Beginnings Vitamin C + Niacinamide Dual Serum DV’s pick!
Best for: Fighting early signs of ageing with little effort
Combining a Vitamin C Serum and a Niacinamide Serum in one bottle, this serum gives you the power of two serums in one pump. Sounds perfect for lazy girls and those who are time-strapped!
Besides skin brightening and improving collagen synthesis, this serum also fights free radicals and soothes redness. The result? More radiant, firmer skin, that looks more youthful.
What’s more, Niacinamide helps soothe the irritation that Vitamin C sometimes have on the skin, so you get a comfortable sensation.
As a bonus, it comes with a citrus scent that makes your anti-ageing routine an absolute treat!
But Better Brighter Beginnings Vitamin C + Niacinamide Dual Serum retails for S$48 (U.P S$72) at Shopee.
Estee Lauder Advanced Night Repair Serum
Best for: Tired skin that needs repair
A timeless favourite, this anti-ageing serum is known for its hydrating, cushiony feel, and visible impact on fine lines.
Using a hyaluronic acid-based complex with antioxidants, this supports overnight skin repair.
You’ll love that it has no tingling nor tightness, just “well-rested skin” the next morning.
Estee Lauder Advanced Night Repair retails for S$258 (75ml) at all Estee Lauder boutiques and counters, as well as Sephora. Note that there are many sizes available at different prices.
Dr. Dennis Gross Advanced Retinol + Ferulic Texture Renewal Serum
Best for: Texture refinement
Powered by Retinol, Bakuchiol, Rambutan, and Ferulic Acid, this anti-ageing serum helps build proteins and reduces the appearance of fine lines.
However, what it’s probably best known for is its ability to improve skin texture, so it looks smoother.
To ensure it feels comfortable on the skin, the serum also includes Squalane and Hyaluronic Acid to boost hydration.
Dr. Dennis Gross Advanced Retinol + Ferulic Texture Renewal Serum retails for S$129 at at Sephora.
The Ordinary Buffet + Copper Peptides 1%
Best for: Layering in multi-step routines
Using six well-studied peptide technologies, skin-friendly amino acids, and multiple hyaluronic acids, this offers an all-in-one solution.
It promises to improve the appearance of lines, supports overall elasticity, and firms skin.
The Ordinary Buffet + Copper Peptides 1% retails for S$60 at Sephora.
La Roche-Posay Redermic Retinol B3 Serum
Best for: Retinol beginners
Using a unique form of retinol called Redermic R, this anti-ageing serum is formulated with sensitive skin in mind.
In other words, you’ll likely be able to tolerate it even if you are new to retinol, which tends to irritate skin.
La Roche-Posay Redermic Retinol B3 Serum retails for S$84.70 at Watsons.
Olay Regenerist Retinol24 Night Serum
Paula’s Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment
Best for: Delicate skin that still wants results
While most people use Bakuchiol as a replacement for Retinol, this anti-ageing serum combines both as the former stabilises the latter, to deliver results without irritation. Together, they help target fine lines, wrinkles, uneven skin tone, enlarged pores, and rough texture.
This serum also contains peptides, which can help strengthen skin and combat sagging.
Paula’s Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment retails for S$98 and at Sephora.
When To Start Using Anti-Ageing Serum?
You don’t have to wait for fine lines to show before reaching for an anti-ageing serum. Most dermatologists recommend starting in your mid-to-late 20s or early 30s, when collagen production naturally begins to slow.
That said, it’s never too late to add one into your routine. Think of it as a preventive step; targeting early signs of ageing before they become more noticeable, while also giving your skin a boost in hydration, firmness, and glow.
What To Look For in an Anti-Ageing Serum?
Not all serums are created equal, so check the ingredient list.
Look for powerhouse actives such as these:
- Retinol: Increase cell turnover
- Bakuchiol: Consider this as a gentler alternative to retinol
- Vitamin C: Brighten and improve collagen synthesis
- Niacinamide: Strengthen skin barrier
- Peptides: Support collagen synthesis
- Hyaluronic acid: Deep hydration to prevent fine lines
How To Use an Anti-Ageing Serum?
- Apply your anti-ageing serum after cleansing and before moisturising – ideally on slightly damp skin for better absorption.
- Use two to three drops or one full pump (depending on your serum’s container) and gently press it into your face and neck using your fingertips.
- Consider using it together with a face lifting tool if you have one.
