Imagine a skincare solution that truly does it all – a product that not only tackles fine lines, redness, and texture issues, but actively repairs the skin from the inside out.
For most of us, the quest for that holy grail has felt almost impossible. That was until the new Lancôme Génifique Ultimate Serum entered the chat.
This cutting-edge formula promises not only to enhance skin’s resilience against daily damage but also to reverse visible signs of ageing and stress in just one week. Too good to be true? We challenged 10 Daily Vanity readers to put its claims to the test.
Read on for their full reviews.
About Lancôme Génifique Ultimate Serum

The Lancôme Génifique Ultimate Serum is a powerful formula that redefines the boundaries of skin renewal, combining nearly three decades of repair science with the revolutionary Beta Glucan-CM technology.
Each dropper delivers:
- 90 trillion Beta Glucan-CM: Inspired by the medical field to accelerate skin recovery like never before, and more potent than hyaluronic acid.
- Hyaluronic acid: Replenishes and plumps the skin.
- Licorice extract: Soothes the skin and reduces redness.
- Lancôme’s signature pre- and probiotic fractions: Strengthens your skin’s microbiome.
After just one week of use, expect improvements in texture, resilience, and overall radiance, with 100% of users noting visibly enhanced skin quality*.
And it’s not just self-assessments that tell the story – clinical results show a 25% reduction in redness**, a 30% decrease in fine lines***, and a 40% boost in skin smoothness***, making this serum an essential for anyone looking to reverse signs of skin damage and amplify their natural glow.
Designed with a high-precision dropper for the perfect dose, Génifique Ultimate Dual-Repair is also formulated with 97% naturally derived ingredients and packaged in a refillable 50ml format, marrying innovation with sustainability.
Suitable for all skin types – even the most sensitive – this serum is a fast-absorbing, deeply rejuvenating solution for lasting, youthful radiance.
*Clinical grading after one week on 50 women
**Clinical study of 43 women subjected to 35 minutes of capsaicin aggression after 27 days of usage
***Clinical study on 50 women in two months
Lancôme Génifique Ultimate Serum retails for S$145 (30ml), S$204 (50ml), S$173 (50ml refill), and S$359 (115ml) at Lancôme boutiques and counters, Lancome.com.sg, Lazada, and Sephora.
Lancôme Génifique Ultimate Serum Reviews: 10 Readers Share Their Honest Opinions
Lancôme Génifique Ultimate Serum
Summary
Across multiple first impressions of Lancôme Génifique Ultimate Serum, our readers described it as lightweight, silky, and quickly absorbing, with a velvety, non-sticky texture that felt refreshing on the skin.
Many noted how their skin felt instantly soothed and hydrated, with some experiencing a subtle glow and plumpness right after the first use. Several readers also appreciate the natural, pleasant scent.
By the end of one week, the readers reported noticeable improvements in skin texture and hydration, describing their skin as softer, more refined, and visibly smoother. Many highlight a newfound radiance, with some seeing reductions in redness, acne scars, and blemishes, while others note that fine lines appeared softened and pores seemed minimised.
Overall, the readers feel the serum effectively balances moisture levels, creating a healthy, dewy complexion without a greasy feel, and many mentioned the serum’s performance in calming their skin as well.
The serum’s long-term benefits stand out in its ability to even skin tone, enhance elasticity, and boost overall skin health, with some readers calling it the best serum they’ve tried.
Emiley, 27
Skin type: Combination-oily
Skin concerns: Uneven skin tone, redness, fine lines/wrinkles, textured skin (e.g. small, rough bumps), visible/enlarged pores, blackheads/whiteheads, dark under-eye circles

My first impression of Lancôme’s Génifique Ultimate Serum was how incredibly lightweight and watery it felt – it absorbs in seconds, leaving no greasiness behind. After just one use, my skin looked brighter and more radiant, feeling moisturised but not sticky or heavy.
I noticed an immediate smoothness to my skin’s texture, and it left such a positive impression that I was excited to keep using it.
After a full week, the benefits only grew stronger. My skin felt noticeably smoother and more refined, with an increase in hydration and elasticity. Fine lines appeared softened, blemishes and redness were reduced, and my complexion looked fresher and more youthful.
Unlike other serums I’ve tried, this one managed to keep my skin both radiant and hydrated while reducing the appearance of fine lines. Overall, this serum has helped elevate my skin’s radiance, smoothness, and overall health in just seven days.
Teresa, 27
Skin type: Dry, combination-oily
Skin concerns: Dull skin, uneven skin tone, damaged skin barrier, fine lines/wrinkles, textured skin (e.g. small, rough bumps), dehydrated skin, visible/enlarged pores, blackheads/whiteheads, acne/blemishes, dark under-eye circles

From the first application, the Lancôme Génifique Ultimate Serum impressed me with its silky, velvety texture that absorbed almost instantly. It left my skin feeling refreshed, deeply hydrated, and with a healthy plumpness that had me excited to keep using it.
The lightweight formula didn’t leave any residue, and within a few days, I could already see a brightening effect that made my complexion look more vibrant.
After a week, my skin felt softer, smoother, and more hydrated than it had with other serums. My pores appeared smaller, fine lines were noticeably softened, and even some pigmentation had started to fade, giving me a more even skin tone.
The serum also strengthened my skin barrier without clogging pores, making it both effective and gentle. It’s the best serum I’ve tried, and with its quick-absorbing, fuss-free formula, it’s become a staple in my routine for radiant, healthy skin.
Kathlynn, 27
Skin type: Combination-oily
Skin concerns: Fine lines/wrinkles, textured skin (e.g. small, rough bumps), visible/enlarged pores, dark under-eye circles

The Lancôme Génifique Ultimate Serum has a similar scent to another serum I use, but it absorbs even faster, with a watery, lightweight texture that leaves my skin plump and brighter almost immediately.
It feels light and non-greasy, making it a fuss-free addition to my routine, especially on busy days.
After a week, my skin felt softer, more supple, and hydrated, with a noticeable boost in radiance and an evened-out complexion. Redness was reduced after a few days, and my skin felt stronger and healthier overall, all without any irritation.
This serum has become a refreshing, easy-to-use staple in my routine, helping my skin feel resilient and revitalised.
Jasmine, 30
Skin type: Combination-dry
Skin concerns: Dull skin, uneven skin tone, fine lines/wrinkles, textured skin (e.g. small, rough bumps), dark under-eye circles

Upon first use of the Lancôme Génifique Ultimate Serum, I was immediately impressed by how fresh it smelled and how quickly it absorbed into my skin. The texture is lightweight and gel-like, leaving no sticky residue behind, which is a huge plus.
After a week, the results spoke for themselves: my skin felt noticeably softer, smoother, and more hydrated. There was a visible boost in radiance and an improvement in skin elasticity, with fine lines looking less noticeable and a reduction in redness.
My complexion appeared brighter and healthier, with a youthful, dewy look.
Fang Jing , 35
Skin type: Combination-oily, sensitive
Skin concerns: Dull skin, uneven skin tone, redness, damaged skin barrier, fine lines/wrinkles, textured skin (e.g. small, rough bumps), dehydrated skin, visible/enlarged pores, blackheads/whiteheads, acne/blemishes, dark under-eye circles

I’m impressed that the silky texture of Lancôme’s Génifique Ultimate Serum absorbs quickly, leaving my skin feeling smooth and refreshed. This lightweight, non-greasy formula is perfect for daily use, and the luxurious packaging is a bonus.
After seven days of using the serum, my complexion is transformed! My skin looks smoother, brighter, and more radiant. Fine lines and wrinkles appear reduced, and pores are minimised.
Hydration levels have improved, leaving my skin feeling plumper and firmer. Redness has also decreased, revealing a more even-toned complexion.
Compared to other serums, it absorbs faster, feels lighter, and enhances radiance. Suitable for sensitive skin, it delivers noticeable improvements in elasticity, firmness, and brightness, making it my go-to serum.
Loving the noticeable improvements and I look forward to continued results!
Tracy, 36
Skin type: Combination-dry, sensitive
Skin concerns: Dull skin, uneven skin tone, redness, dehydrated skin, visible/enlarged pores, blackheads/whiteheads, dark under-eye circles

The Lancôme Génifique Ultimate Serum has a lightweight texture which absorbs speedily into the skin. Scent was faint but pleasant!
Although there was no distinct difference in terms of appearance after a single use, my skin felt more hydrated and supple, almost as though there was a boost of moisture pumped and locked into my skin.
My skin tone was quite dull and uneven when I got off a long flight, and I looked very tired. After seven days, I noticed that my skin tone became fairer, brighter and more even. My pores were smaller, and the redness of my cheeks also subsided.
Each time I applied the serum, my skin felt plump with moisture. Over time, I looked rejuvenated and radiant with continuous usage.
I had high expectations for this product since it belongs to an upmarket brand, and I’m pleased to see that it has delivered what it promised! Overall, I enjoyed using this product tremendously and will continue till its last drop.
Cheryl, 34
Skin type: Normal, sensitive
Skin concerns: Uneven skin tone, redness, dehydrated skin, dark under-eye circles

My first impression of Lancôme Génifique Ultimate Serum was very positive. It absorbed effortlessly, with a light, natural scent that didn’t overpower.
The gel-like, lightweight texture felt calming on my skin, leaving it balanced and comfortable without any residue. My skin felt moisturised but not greasy, and I appreciated how quickly I could layer my moisturiser over it.
After seven days, I noticed a refined texture and an even skin tone, with my skin feeling both healthier and stronger. The serum managed to improve smoothness within just two days, and by the end of the week, I saw an increase in elasticity and a visible glow.
Compared to other serums, it feels gentle yet effective, and I can see the potential for longer-term benefits, especially for postpartum skin concerns as a busy working mum. I’m excited to keep using it and would love to see even more long-term results.
Penny, 35
Skin type: Oily
Skin concerns: Dull skin, uneven skin tone, fine lines/wrinkles, textured skin (e.g. small, rough bumps), visible/enlarged pores

From my first application of Lancôme’s Génifique Ultimate Serum, I was impressed by how quickly it absorbed, leaving my skin feeling soft, hydrated, and refreshed without any stickiness.
The lightweight, silky texture instantly made my skin look plumper and brighter, and my fine lines appeared less noticeable. It felt soothing on my skin, making it a pleasure to use every day.
After a week, the results were undeniable – my skin looked healthier, smoother, and more radiant than it had in a long time. My pores appeared smaller, my skin tone was more even, and blemishes and redness had visibly reduced.
This serum has done more for my skin than any other product I’ve tried, and I even received compliments on my improved complexion. The boost in hydration, clarity, and firmness makes Génifique Ultimate a standout in my skincare routine, and it’s easily the best serum I’ve ever used.
Peixin, 30
Skin type: Combination-oily, sensitive
Skin concerns: Dull skin, uneven skin tone, redness, textured skin (e.g. small, rough bumps), visible/enlarged pores, blackheads/whiteheads, acne/blemishes

From the first application, I noticed how lightweight and silky Lancôme’s Génifique Ultimate Serum felt, absorbing almost instantly without any sticky residue.
My skin felt immediately hydrated and soothed, and I didn’t experience any irritation, which was a big plus. It also provided a balanced, non-greasy feel, making it easy and comfortable to layer with other products in my routine.
After using it consistently for seven days, I saw impressive results: my skin felt smoother, and the texture looked refined and plumper. I noticed a subtle glow that’s hard to find with most serums, along with reduced redness and a more even skin tone.
My acne scars even appeared lighter, and my pores seemed smaller, which gave my complexion an overall fresh, radiant look.
Min Yi, 31
Skin type: Combination-dry
Skin concerns: Dull skin, damaged skin barrier, dark under-eye circles

I noticed the Lancôme Génifique Ultimate Serum has a silky, lightweight texture and a pleasant, subtle scent. It absorbed in seconds without leaving any sticky residue, which was great for my dehydrated skin.
While I didn’t see immediate, dramatic changes, I could feel a boost in hydration, and the non-greasy formula left my skin moisturised and refreshed.
After a week, my skin looked smoother and felt more refined and soothed. By day six, I noticed an increase in radiance, and fine lines appeared slightly softened, which made my skin look healthier overall.
While hydration was my primary concern, I plan to continue using it long-term to see if it improves pigmentation. Compared to other serums, this one has a natural scent and doesn’t feel oily, making it ideal for my hydration and anti-ageing needs.
Lancôme Génifique Ultimate Serum retails for S$145 (30ml), S$204 (50ml), S$173 (50ml refill), and S$359 (115ml) at Lancôme boutiques and counters, Lancome.com.sg, Lazada, and Sephora.
